

On December 31, 2022, the official website of the Ministry of Science and Technology announced a summary of the public notification of the results of the investigation and handling of medical research integrity cases in some universities.
1. The paper "Schizandrin A Protects Human Retinal Pigment Epithelial Cell Line ARPE-19 against HG-Induced Cell Injury by Regulation of miR-145" by Wan Guangming from the First Affiliated Hospital of Zhengzhou University as the corresponding author and Dong Yi as the first author. After investigation, it was found that there were behaviors such as buying and selling picture data and improper signature in this paper. The unit dealt with Dong Yi in the following ways: scientific research integrity admonishment conversation, included in the scientific research dishonesty record database, the whole hospital circulated criticism, disqualification for 3 years, postponing the promotion of professional titles for 2 years, cancellation of all levels of scientific and technological plans to declare financial support (Projects), science and technology awards, and scientific and technological talents for 3 years; Wan Guangming will be dealt with as follows: cancel the qualifications for 3 years of evaluation and evaluation, and cancel the application of financial funds to support scientific and technological plans (projects), scientific and technological awards, scientific and technological talents, etc. 2 years of qualification, 2 years of disqualification for graduate admissions.
(Notification link: https://www.zdyfy.com/cxjs/content_24215)
2. Wan Guangming from the First Affiliated Hospital of Zhengzhou University is the corresponding author, Qian Cheng and Liang Shenzhi are the co-first authors of the paper "Salidroside induces high-glucose-induced injury in retinal pigment epithelial cell line ARPE-19 by down-regulation of miR- 138". After investigation, it was found that there were behaviors such as buying and selling picture data and improper signature in this paper. The work unit dealt with Qian Cheng as follows: scientific research integrity admonition talk, included in the scientific research dishonesty record database, the whole hospital circulated criticism, disqualification for 3 years, revoked his title of deputy chief physician, postponed his promotion title for 2 years, and canceled his financial declaration. Qualifications for all levels of scientific and technological plans (projects), scientific and technological awards, and scientific and technological talents supported by funds for 3 years; Liang Shenzhi will be dealt with as follows: scientific research integrity admonishment talk, included in the scientific research dishonesty record database, the whole hospital will be criticized, and the qualification for evaluation and evaluation will be cancelled. 1 year, postponing the promotion of professional titles for 1 year, canceling the qualifications for all levels of scientific and technological plans (projects), scientific and technological awards, and scientific and technological talents supported by financial funds for 1 year; Qualifications for all levels of science and technology plans (projects), science and technology awards, and scientific and technological talents declared for financial support are 2 years, and the qualifications for postgraduate enrollment are canceled for 2 years.
(Notification link: https://www.zdyfy.com/cxjs/content_24215)
3. The paper "Long noncoding RNA HAGLROS regulates apoptosis and autophagy in Parkinson's disease via regulating miR-100/ATG10 axis and PI3K/ Akt/mTOR pathway activation". After investigation, it was found that there were behaviors such as buying and selling picture data and improper signature in this paper. The unit has dealt with Peng Tao as follows: scientific research integrity admonishment talk, included in the record database of scientific research dishonesty, the whole hospital circulated criticism, disqualification for 5 years, postponing the promotion of professional titles for 3 years, cancellation of all levels of science and technology plans for financial support (Project), scientific and technological awards, scientific and technological talents and other qualifications for 5 years, disqualification of postgraduate enrollment qualifications for 5 years; Wan Wencui will be dealt with as follows: scientific research integrity admonishment talk, included in the scientific research dishonesty record database, the whole hospital circulates criticism, cancels the excellent evaluation Qualification for 5 years, postponing the promotion of professional titles for 3 years, canceling the qualifications for all levels of scientific and technological plans (projects), scientific and technological awards, and scientific and technological talents supported by financial funds for 5 years, and canceling the qualifications for graduate student enrollment for 5 years; the following treatment for Lu Hong: cancel The eligibility for first-rate evaluation for 1 year, the cancellation of qualifications for all levels of scientific and technological plans (projects), scientific and technological awards, and scientific and technological talents supported by financial funds for 1 year, and the cancellation of postgraduate enrollment qualifications for 1 year.
(Notification link: https://www.zdyfy.com/cxjs/content_24215)
4. The paper "Physcion 8-O-beta-glucopyranoside exerts protective roles in high glucose-induced diabetic retinopathy via regulating lncRNA NORAD/miR-125" by Qiuming Li as the corresponding author and Wencui Wan as the first author from the First Affiliated Hospital of Zhengzhou University /STAT3 signaling". After investigation, it was found that there were behaviors such as buying and selling picture data and improper signature in this paper. The unit dealt with Wan Wencui as follows: admonishment conversations on scientific research integrity, included in the record database of scientific research dishonesty, the whole hospital notified criticism, canceled the qualification for evaluation and evaluation for 5 years, postponed the promotion of professional titles for 3 years, and canceled the declaration of all levels of science and technology supported by financial funds. Qualifications for planning (projects), scientific and technological awards, and scientific and technological talents for 5 years, and disqualification for postgraduate enrollment for 5 years; Li Qiuming will be dealt with as follows: cancel the qualification for evaluation and evaluation for 1 year, and cancel the application of financial funds to support scientific and technological plans (projects) at all levels ), science and technology awards, scientific and technological talents and other qualifications for 1 year, and the qualification for postgraduate enrollment is canceled for 1 year.
(Notification link: https://www.zdyfy.com/cxjs/content_24215)
5. The paper "Physcion 8-O-β-glucopyranoside induced ferroptosis via regulating miR-103a-3p/GLS2 axis in gastric cancer" by Liu Bingrong from the First Affiliated Hospital of Zhengzhou University as the corresponding author and Niu Ying as the first author. After investigation, it was found that there were behaviors such as buying and selling picture data and improper signature in this paper. The unit has dealt with Niu Ying as follows: scientific research integrity admonishment talk, included in the scientific research dishonesty record database, the whole hospital circulated criticism, canceled the qualifications for evaluation and evaluation for 5 years, postponed the promotion of professional titles for 3 years, and canceled the declaration of all levels of scientific and technological plans supported by financial funds (Project), scientific and technological awards, scientific and technological talents and other qualifications for 5 years; Liu Bingrong will be dealt with as follows: scientific research integrity admonition talk.
(Notification link: https://www.zdyfy.com/cxjs/content_24215)
6. The paper "Silencing UNC5B antisense lncRNA 1 represses growth and metastasis of human Colon cancer cells via raising miR-622" was written by Li Xia from the First Affiliated Hospital of Zhengzhou University as the corresponding author and Zhang Yan from Huaihe Hospital of Henan University as the first author. After investigation, it was found that there was buying and selling of papers in this paper. Li Xia didn't know. Huaihe Hospital of Henan University dealt with Zhang Yan as follows: disqualification for undertaking financial support projects for 3 years. As nominators or recommenders, nominated or recommenders, review experts, etc.
(Notification link: https://kyc.henu.edu.cn/info/1289/11969.htm)
7. The paper "LncRNA MEG3 inhibits HMEC-1 cells growth, migration and tube formation via sponging miR-147" by Jianshi Du as the corresponding author and Dejun Xu as the first author of Sino-Japanese Friendship Hospital of Jilin University. After investigation, it was found that the thesis had the behavior of buying and selling the data of the thesis . The unit has dealt with Xu Dejun as follows: notice of criticism, disqualification of science and technology planning projects (special projects, funds, etc.) For 12 months, it is forbidden to participate in the qualification review of graduate students for 1 year, and as a registered graduate student, it will be given the sanction of probation; Du Jianshi does not know about the thesis and will not be dealt with.
(Notification link: http://jluxfjs.jlu.edu.cn/content.jsp?urltype=news.NewsContentUrl&wbtreeid=1021&wbnewsid=1485)
8. The paper "Long noncoding RNA SNHG7 represses the expression of RBM5 to strengthen metastasis of hepatocellular carcinoma" by Wang Yan of Jilin University Sino-Japanese Friendship Hospital as the corresponding author and Sun Baozhen as the first author. After investigation, it was found that the thesis had the behavior of buying and selling paper data and improper signature. The unit has dealt with Sun Baozhen (additional treatment on the basis of the previous treatment) as follows: notice of criticism, disqualification of scientific and technological planning projects (special projects, funds, etc.) for 6 years, disqualification of various awards and awards for 2 years, cancellation of positions and titles Valid declaration qualification for promotion once, withholding of post allowance for 24 months, prohibition from participating in postgraduate admissions qualification review for 2 years from 2023; the following treatment for Wang Yan (combined with 1 other paper): notice of criticism, cancellation of science and technology plan projects (Special projects, funds, etc.) declaration qualifications for 6 years, disqualification of various awards and appraisal qualifications for 2 years, cancellation of valid declaration qualifications for position and professional title promotion once, withholding post allowances for 24 months, and prohibiting participation in graduate student enrollment qualification examinations from 2023 2 In 2010, the position of deputy chief physician was revoked.
(Notification link: http://jluxfjs.jlu.edu.cn/content.jsp?urltype=news.NewsContentUrl&wbtreeid=1021&wbnewsid=1485)
9. The paper "Long noncoding RNA CASC15 is upregulated in non-small cell lung cancer and facilitates cell proliferation and metastasis via targeting miR-130b-3p" by Wang Wanli of Jilin University Sino-Japanese Friendship Hospital as the corresponding author and Yu Dujuan as the first author The paper "Long non-coding RNA OR3A4 is associated with poor prognosis of human non-small cell lung cancer and regulates cell proliferation via up-regulating SOX4" with Juan Yu as the corresponding author and Ming Zhong as the first author of the China-Japan Friendship Hospital of Jilin University . After investigation, it was found that the two papers had the behavior of buying and selling the data of the papers . The unit has dealt with Du Juan as follows: notice of criticism, disqualification of scientific and technological planning projects (special projects, funds, etc.) From 2023, Wang Wanli will be banned from participating in the qualification examination for graduate enrollment for 2 years; the following treatment will be given to Wang Wanli: notice of criticism, cancellation of application qualifications for science and technology planning projects (special projects, funds, etc.) for 5 years, and cancellation of qualifications for various awards and awards for 2 years , revoked the valid application qualifications for post and professional title promotion once, withheld the post allowance for 12 months, and was prohibited from participating in the postgraduate enrollment qualification review for one year from 2023; Zhong Ming was dealt with as follows: notice of criticism, cancellation of scientific and technological plan projects (special projects, funds, etc. ) declaration qualifications for 5 years, disqualification for various awards and appraisals for 2 years, cancellation of valid declaration qualifications for position and professional title promotion once, post allowance for 12 months, prohibition from participating in the qualification examination for postgraduate enrollment for 1 year from 2023, and revocation of the deputy director Physician duties.
(Notification link: http://jluxfjs.jlu.edu.cn/content.jsp?urltype=news.NewsContentUrl&wbtreeid=1021&wbnewsid=1485)
10. Zhang Wenlei and Li Xingliang from the First Hospital of Jilin University are the co-corresponding authors, and Wang Yan from the China-Japan Friendship Hospital of Jilin University and Jiang Xiaoming from the First Hospital of Jilin University are the co-first authors of the paper "Long noncoding RNA PCAT-1 accelerates the metastasis of pancreatic cancer by repressing RBM5". After investigation, the paper has falsified data . The unit has dealt with Wang Yan (combined with 1 other paper) as follows: notice of criticism, disqualification of scientific and technological planning projects (special projects, funds, etc.) Effectively declare the qualification once, withhold the post allowance for 24 months, prohibit the participation in the postgraduate enrollment qualification review for 2 years from 2023, and revoke the position of deputy chief physician; the following treatment will be given to Jiang Xiaoming: notice of criticism, cancellation of scientific and technological plan projects (special projects, funds, etc. ) declaration qualifications for 5 years, cancellation of various awards and evaluation qualifications for 2 years, cancellation of valid declaration qualifications for position and professional title promotion once, withholding post allowances for 12 months, and prohibiting participation in postgraduate enrollment qualification examinations for 1 year from 2023; Handle as follows: Notification of criticism, cancellation of application qualifications for science and technology planning projects (special projects, funds, etc.) From 2023, it will be prohibited to participate in the qualification review of postgraduate enrollment for one year; Li Xingliang will be dealt with as follows: notice of criticism, cancellation of application qualifications for science and technology planning projects (special projects, funds, etc.) for 5 years, cancellation of various awards and evaluation qualifications for 2 years, cancellation of positions and titles Valid declaration qualifications for promotion once, post allowances withheld for 12 months, and participation in the postgraduate enrollment qualification review for one year from 2023 onwards.
(Notification link: http://jluxfjs.jlu.edu.cn/content.jsp?urltype=news.NewsContentUrl&wbtreeid=1021&wbnewsid=1485)
11. The paper "Knockdown of long non-coding RNA CCAT1 suppresses proliferation and EMT of human cervical cancer cell lines by down-regulating Runx2" written by Li Ruiping, Affiliated Hospital of Jilin University of Medicine, as the first author and corresponding author. After investigation, it was found that the paper had compiled the research process and the experimental results were not credible. The unit dealt with Li Ruiping as follows: cancel the qualifications for professional title and rank evaluation, the qualifications for evaluating the best and the first, and honorary titles for 3 years, and cancel the qualifications for applying for scientific and technological plan projects (special projects, funds, etc.), teaching and research projects, and technology and teaching awards for 3 years.
(Notification link: http://www.jl465.com/detail/1144.html)
12. The paper "Physcion blocks cell cycle and induces apoptosis in human B cell precursor acute lymphoblastic leukemia cells by downregulating HOXA5" was written by Liu Wenjun as the corresponding author and Gao Fei as the first author from the Affiliated Hospital of Southwest Medical University. After investigation, it was found that there were activities such as buying and selling data in this paper. The unit dealt with Liu Wenjun as follows: Contact the magazine to withdraw the manuscript, cancel the qualification to apply for all kinds of science and technology projects at all levels for 3 years, suspend the enrollment of graduate students for 1 year, and cancel the qualification of part-time doctoral supervisor of Jinan University; deal with Gao Fei as follows: revoke the master's degree.
(Notification link: https://www.ahswmu.cn/site/kjb/detail/b8070f2f-b0d3-079b-0a92-ed217179.html)
Thirteen. Xia Yong from the Affiliated Hospital of Shonan University, Fang Qing from the Third Affiliated Hospital of Central South University are the co-corresponding authors, and Mu Guangfu from the Third Affiliated Hospital of Central South University is the first author of the paper "Long noncoding RNA HAGLROS promotes the process of mantle cell lymphoma by regulating miR-100/ATG5 axis and involving in PI3K/AKT/mTOR signal". After investigation, it was found that there were frauds and plagiarism in the paper. Fang Qing and Mu Guangfu didn't know. The Affiliated Hospital of Shonan University made the following treatment for Xia Yong: suspending his qualifications for promotion to higher-level professional and technical positions for 2 years;
(Notification link: https://fsyy.xnu.edu.cn/2021_08/24_11/content-62597.html, https://kxyjb.csu.edu.cn/info/1393/10491.htm)
14. The paper "MicroRNA-30b promotes lipopolysaccharide-induced inflammatory injury and induces autophagy through JNK and NF-κB pathways in HK-2 cells" by Rong Wang as the corresponding author and Lili Zhang as the first author from Shandong First Medical University. After investigation, the paper has tampered with data , forged the email address of the corresponding author , and improperly signed. The unit dealt with Wang Rong as follows: cancel the participation in the current year's appraisal, the first-rate appraisal, the current year's assessment cannot be determined as excellent, and suspend the qualifications for recruiting graduate tutors for one year; Zhang Lili has the following treatment: cancel the doctor's degree application qualification.
(Notification link: https://sr.sdfmu.edu.cn/info/1011/1967.htm)
15. The paper "Baicalin protects human retinal pigment epithelial cell lines against high glucose-induced cell injury by up-regulation of microRNA-145" by Zhao Bojun from Shandong First Medical University as the corresponding author and Dai Chunhua as the first author. After investigation, the paper has tampered with data, forged the email address of the corresponding author , and improperly signed. The unit has dealt with Zhao Bojun as follows: Cancel participation in the current year's evaluation, the priority evaluation, the current year's evaluation cannot be determined as excellent, cancel the qualification for applying for or declaring science and technology plan projects for 5 years, and cancel being a nominee or recommender, nominated or recommender, Qualifications such as evaluation experts for 5 years, the qualifications for graduate tutor enrollment are suspended for 1 year, the appointment of the third-level post is revoked, and the third-level post is downgraded to the fourth-level position;
(Notification link: https://sr.sdfmu.edu.cn/info/1011/1967.htm)
16. The paper "Pioglitazone alleviates oxygen and glucose deprivation-induced injury by up-regulation of miR-454 in H9c2 cells" by Zou Chengwei of Shandong First Medical University as the corresponding author and Sun Nianzi as the first author. After investigation, the paper has ghostwriting , data tampering, falsification of corresponding author's email address, improper signature and other acts. The unit has dealt with Zou Chengwei as follows: cancel the participation in the current year's appraisal, the first-rate appraisal, the current year's assessment cannot be determined as excellent, and suspend the qualifications for recruiting graduate tutors for one year; the following treatment for Sun Nianzi: cancel the doctorate application qualification.
(Notification link: https://sr.sdfmu.edu.cn/info/1011/1967.htm)
17. The paper "miR-132 weakens proliferation and invasion of glioma cells via the inhibition of Gli1s" by Guangming Xu from Shandong First Medical University as the corresponding author and Yuzhi Wang as the first author. After investigation, the paper has tampered with data . The unit has dealt with Xu Guangming as follows: cancel the participation in the current year's evaluation, and the current year's evaluation cannot be determined as excellent, cancel the qualification for applying for or declaring science and technology plan projects for 5 years, and cancel being a nominee or recommender, nominated or recommender, Qualifications such as evaluation experts for 5 years, and the qualifications for graduate tutor enrollment are suspended for 1 year; Wang Yuzhi will be dealt with as follows: revoke his doctorate.
(Notification link: https://sr.sdfmu.edu.cn/info/1011/1967.htm)
18. The paper "Physcion 8-O-β-glucopyranoside Suppresses Tumor Growth of Hepatocellular Carcinoma by Downregulating PIM1" with Tian Xingsong from Shandong First Medical University as the corresponding author and Wang Qinggang as the first author. After investigation, the paper has tampered with data , submitted on behalf of others, falsified the email address of the corresponding author, and improperly signed. The unit has dealt with Tian Xingsong as follows: cancel the participation in the current year's evaluation, the first evaluation of the best, the current year's evaluation cannot be determined as excellent, the qualification for applying for or declaring science and technology plan projects for 5 years, and canceling as a nominee or recommender, nominated or recommender, Qualifications such as evaluation experts for 5 years, the qualifications for graduate tutor enrollment are suspended for 1 year, and one project of Jinan Science and Technology Development Plan is revoked; Wang Qinggang is dealt with as follows: the doctorate degree is revoked.
(Notification link: https://sr.sdfmu.edu.cn/info/1011/1967.htm)
(Original title "Summary of Public Notification of Investigation and Handling Results of Medical Research Integrity Cases in Some Universities (December 26, 2022)")