On October 27, the "China Science and Technology Breakthrough in the Computing Power Era 2022 Science and Technology Leaders Forum" hosted by The Paper and guided by Shanghai Paper Industry Group was held in The Paper's North Bund World Meeting Room Studio. This forum invites leaders of science and technology innovation at the forefront of the industry to discuss important issues such as how companies, regions and even countries can accumulate data resources, improve computing power, and optimize the computing power industry.

China's layout in the era of computing power

Zhang Hongtao, chief engineer of Shanghai Economic and Information Commission, delivered a speech at the conference

Zhang Hongtao, chief engineer of the Shanghai Municipal Commission of Economy and Information Technology, said that the report of the 20th National Congress of the Communist Party of China specifically pointed out that it is necessary to deeply implement the strategy of rejuvenating the country through science and education, the strategy of strengthening the country with talents, and the strategy of innovation-driven development, open up new fields and new tracks for development, and constantly shape new development momentum. New advantages; it is necessary to build a new development pattern, focus on promoting high-quality development, and build a modern industrial system. In this regard, Shanghai has achieved a certain first-mover advantage. During the "14th Five-Year Plan" period, Shanghai proposed to develop a new "3+6" industrial system; this year, Shanghai has formulated action plans and plans for new tracks such as green and low-carbon, metaverse, smart terminals, and digital economy; not long ago, The municipal government also issued the Action Plan for Shanghai to Build Future Industrial Innovation Highlands to Develop and Expand Future Industrial Clusters, clearly proposing to build future intelligent industrial clusters, focusing on the development of intelligent computing, general AI, XR technology, etc., and deploying AI + drug research and development, AI + new materials and other applications. These are the key directions of the computing power era, and Shanghai is focusing on the layout. For the future development of Shanghai in this area, firstly, it is necessary to strengthen the research on key core technologies, promote the research and development of key technologies such as high-end chips, computing architecture, core algorithms and big data, and improve the basic industrial capabilities and the modernization level of the industrial chain. The second is to build a computing power industry ecosystem, strengthen the main role of enterprises in innovation, give play to the role of leading enterprises, focus on promoting the development and application of "computing power + industry", and enhance the efficiency of computing power application empowerment. The third is to strengthen the innovation of industry-university-research integration, support enterprises to form innovation consortia with universities and research institutes, break through the key core technologies and common technologies that restrict industrial development, and accelerate the transformation of scientific and technological achievements.

Today, the development of human productivity is entering the fourth era - the era of computing power. Computing power not only facilitates the research of biomedical innovative drugs in biomedicine, but also leads industry breakthroughs in the development of the Metaverse, profoundly changing human production methods, living patterns and scientific research paradigms. Liu Yonggang, president and editor-in-chief of The Paper, said that as the world's largest manufacturing country, China's position and role in the global innovation landscape have undergone new changes in the past decade. China is not only an important participant in international frontier innovation, but also a joint solution Important contributor to global issues. Computing power has increasingly become the foundation of scientific and technological progress and economic and social development, representing the development level of human intelligence. The Paper, as an influential media, needs to be an active responder, report more attempts at technological innovation and institutional innovation, listen to more research and suggestions from different levels, and cooperate with more responsible and active people. institutions and characters stand together.

Keynote Speech: How Algorithms Enable Advances in Biology and Metaverse

Gao Yiqin, Professor of the School of Chemistry and Molecular Engineering, Peking University and Deputy Director of the Department of Science, Peking University, delivered an online keynote speech "Application of Deep Learning in Biomolecular Research - Problems, Methods and Implementation of Software and Hardware Architecture"

In the field of biological sciences, what changes have been brought about by the rapid development of artificial intelligence? Around this issue, Gao Yiqin, professor of Peking University School of Chemistry and Molecular Engineering and deputy director of Peking University's Department of Science, gave a speech on "Deep Learning Applied to Biomolecular Research - Problems, Methods and Implementation of Software and Hardware Architecture", sharing his team's use of computer simulations. Methods To screen and design drug molecules. He believes that high-throughput molecular simulation technology can be realized in a relatively short period of time. Using these methods, we can deeply integrate scientific computing and data-based algorithms, and finally realize multi-sensing simulation tools.

Xu Jinbo, founder of Molecular Hearts and a tenured professor at the Toyota Institute of Computing Technology in Chicago, delivered an online keynote speech "AI Subverts Protein Structure Prediction and Changes the Research Paradigm of Molecular Biology"

The investigation and classification of large amounts of biological data was once considered a challenge, but today artificial intelligence provides powerful tools for it. Xu Jinbo, founder of Molecular Hearts and a tenured professor at the Toyota Institute of Computing Technology in Chicago, said in a keynote speech titled "AI Subverts Protein Structure Prediction and Changes the Research Paradigm of Molecular Biology" that the problem of protein structure prediction has been studied for fifty or sixty years. , but there hasn't been a good solution before. The research process of protein structure prediction can be roughly divided into three stages: the first stage is mainly to do energy optimization; the second stage is to use traditional machine learning to predict its three-dimensional structure based on the amino acid sequence of the protein; the most recent stage , that is, the most successful method, mainly deep learning, which is usually called artificial intelligence, can predict the structure of proteins very well.

Yuan Yu, chairman-designate of IEEE Standards Association and co-founder of Metaverse innovation empowerment and industry incubation platform VerseMaker, delivered an online keynote speech "Digital 5.0: Metaverse Trends, Challenges and Roadmap"

In the past two years, "metaverse" has become one of the hottest technological concepts. What exactly is "metaverse"? How will it change our lives? "Digitization 5.0: Metaverse Trends, Challenges and Roadmap" by Yuan Yu, chairman-elect of the IEEE Standards Association and co-founder of VerseMaker, a metaverse innovation empowerment and industry incubation platform, shows us the future. He believes that the metaverse is an experience. This universe is built on numbers and has three forms. The first is a universe that is different from our current universe, which we usually call virtual reality; the second is the current universe. The digital expansion of , also known as augmented reality; the third is the digital counterpart of the present universe, also known as the digital twin, which are the three main forms of the metaverse. As for the development of the metaverse, Yuan Yu believes that there will be three major challenges in the future. The first is perception and interaction, the second is the virtual world, and the third is the interaction between virtual objects and the real world. These require This is achieved through advances in technologies such as brain-computer interfaces, computer graphics, and XR.

Roundtable Salon: Innovative Drug R&D and Nuggets Metaverse

Roundtable Salon "Research and Development of Innovative Drugs in the Era of Large Computing Power": Moderator Li Yuequn (first from left) discusses with Ma Jianpeng (second from left), Xue Guirong (second from right), and Shen Haifa (first from right)

In the first round-table salon session in the second half of the forum, three science and technology leaders from academia and industry discussed "Innovative Drug Research and Development in the Era of Large Computing Power" with The Paper. The three leaders of science and technology innovation are Ma Jianpeng, Dean of Fudan University's Institute of Complex Systems and Multiscale, Xue Guirong, Founder and CEO of Tianrang, and Shen Haifa, Co-Founder and CTO of Simicrobe. The host of the roundtable forum is the Macro News Department of The Paper and Finance News Director Li Yuequn.

Last year, Deepmind open sourced Alphafold2, which has greatly promoted the entire structural biology and industry. This may be the biggest revolutionary factor for biomedicine in the field of AI. The three guests generally believed that Alphafold2 has indeed brought great assistance to protein structure prediction and greatly promoted the progress of the biomedical industry. However, it is still necessary for China to develop its own set of artificial intelligence algorithms, increase the speed of the combination of biomedicine and artificial intelligence, and attach importance to the education and training of talents in this field. Those who understand both AI and biology may lead the way in the future. Development of new drugs.

The three experts have their own ideas for the future. Ma Jianpeng said: "We must realize that now is the time to really ask what the limitations of AI are. No matter how strong this Alphafold2 is, it has not exceeded the experimental accuracy so far." Xue Guirong said, "The future competition may be It is computing power, and the competition for computing power is very critical. At present, the computing power of AI in the biological field accounts for less than 5%, and there is still a great room for improvement in the future, and it is hoped that more human disease problems will be solved.” As a practitioner in the pharmaceutical industry , Shen Haifa gave an example of mRNA drugs: "Before the new crown, we focused on the research and development of tumor therapeutic mRNA, so in the past two years, we have also used some of our previous experience and some results of research with other companies. For the design of our new crown vaccine ... there are many things to do next, can treat tumors, can treat rare diseases, can treat a series of other diseases." He said that in this process, the addition of AI has greatly improved the entire development speed.

Roundtable Salon "Nuggets Yuan Universe": Moderator Shao Wen (first from left) discusses with Zhao Xing (second from left), Chen Xu (first from right), and Liu Zhiqiang (online connection)

The second roundtable salon of the forum, with the theme of "Nuggets Metaverse", further explored the opportunities and challenges in the "Metaverse" world. Zhao Xing, professor of Fudan University and dean of the Joint Research Institute of Metaverse and Virtual-Reality Interaction, Chen Xu, founder of MetaZ, a think tank of Metaverse, Liu Zhiqiang, CTO of product Jimu, a product of Yingyu Group, and head of the Web3.0 project of Yingyu Group participated in the discussion. The host of the roundtable salon was Shao Wen, an observer of The Paper Metaverse.

All three guests believed that at present, there is no unified understanding in the industry about what the metaverse is. The direction defined by Meta is not necessarily the mainstream direction in the future, but only represents a possibility. The birth of the metaverse is a key stage in the process of a historic turning point for human beings from the survival of physical space to the life of digital space, but the whole process is full of countless possibilities.

Which businesses in the Metaverse are most likely to land and take off? Zhao Xing believes that there are already many landing scenarios in the direction of digital twins, and the game industry has accumulated a lot of technology in the promotion of the metaverse. As an in-depth participant in the industry, Chen Xu believes that "just like the Internet, the use and scale of C-end users are the real explosion points of this industry, and the ultimate growth depends on the C-end." And Liu Zhiqiang shared His entrepreneurial idea: "Like our Ying Universe company, we may start from solving a minimal need, for example, we may be better at socializing and entertainment, we will start from socializing and entertainment, and then continue to expand our entire The layout of the virtual world. We think this may be more suitable for medium-sized enterprises like ours or some small enterprises to land and try, so that the probability of success will be higher and the probability of failure will be lower.”